Effect of stress on wound healing
Effect of stress on wound healing: Stress may as well be referred to as a multidimensional concept since it comprises of physiological, psychological as well as social factors. Stress emanating from physiology aspects may result in high cortisol hormone levels, which might lead to an increased rate of heartbeat as well as blood pressure, therefore impacting negatively on the immunity. Research that entails biopsy wounds that have been experimentally induced has shown that a relationship exists between stress and wound healing that has been delayed.
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Cytokines that are released by the recruited cells control the capacity of the fibroblasts and epithelial cells to modify the tissue that are damaged. IL-1 produced following a tissue injury may control the production, release, as well as stimulation of metalloproteinase (MMP2) that are significant during the destruction as well as the wounds’ remodeling. IL-1 as well regulates fibroblast chemotaxis in addition to the generation of collagen. Furthermore, IL-1 encourages the production of additional cytokines that are significant for the healing of the wound, together with IL-2, IL-6, as well as IL-8.