Determinants of switching from peritoneal to hemodialysis in preserving renal function in ESRD patients

Determinants of switching from peritoneal to hemodialysis in preserving renal function in ESRD patients

Determinants of switching from peritoneal to hemodialysis in preserving renal function in ESRD patients

Determinants of switching from peritoneal to hemodialysis in preserving renal function in ESRD patients: End-stage renal disease (ESRD) is an economic, social, as well as medical burden; but with the advent of peritoneal dialysis (PD) and hemodialysis (HD) therapies, ESRD is becoming manageable.  However, while PD and HD have shown great promise, there are limitations with the success of these techniques resulting in residual renal failure (RRF); especially for patients on PD (Hoshi, Nakamoto & Kanno, 2008; McIntyre, 2008).

Recent studies by Stanley (2010), Shen et al. (2012) and Suzuki et al. (2012) suggest that a switch from PD to HD may enhance patient dialysis outcomes, but these studies were performed on a limited pool of patients.

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This study will use secondary data retrieved from Fresenius Medical Care facility (http://www.fmcna.com/fmcna/index.htm) dialysis repository that will allow the investigator to determine whether social factors (age and gender) and medical conditions (diabetes and cardiovascular diseases) play a role in preservation of renal function.

The researcher chose to use data from the facility because Fresenius has a large secondary data source of 128,482 dialysis patients from across the US which is more representative of the general dialysis population.  The study will utilize a sample of at least 9600 patients drawn from a population of 128,482 patients who had or are undergoing dialysis.  The study will utilize the data for patients with diabetes and cardiovascular disease across all ages and genders.

References
Brener, Z. Z., Thijssen, S., and Kotanko, P. (2011).The impact of residual renal function on hospitalization and mortality in incident hemodialysis patients. Blood Purification, 31, 243–251.

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